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Ofloxacin


Generic Name: Ofloxacin

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Tablets

Ofloxacin belongs to a group of broad spectrum antibiotics called the quinolones. It works by entering the bacterial cell and inhibiting a chemical called DNA-gyrase which is involved in the production of genetic material (DNA). This therefore prevents the bacteria from reproducing and their growth is stopped.

Ofloxacin is effective against several types of bacteria that tend to be resistant to other commonly indicated antibiotics. Ofloxacin is indicated to treat a wide range of infections, including: infections of the chest, urinary tract. Ofloxacin is also indicated as a single dose treatment for gonorrhoea.

Ofloxacin is one of a group of drugs known as quinolone antibiotics.

Ofloxacin is indicated to treat a variety of infections including chest and urinary tract infections. It works by killing or preventing the growth of the bacteria causing the infection.

Ofloxacin is available in tablet and infusion forms.

Antibiotic


Ofloxacin is an antibiotic. Ofloxacin tablets have been indicated effectively to treat lower respiratory tract infections, including:
- Skin;
- Sexually transmitted diseases (except syphilis);
- Prostate gland;
- Pelvic inflammatory disease;
- Infections of the urinary tract;
- Chronic bronchitis and pneumonia;

Ofloxacin Otic solution is indicated to treat ear infections.

Ofloxacin kills a variety of bacteria and is frequently indicated to treat infections in many parts of the body. However, you should stop taking the drug and notify your doctor immediately at the first sign of a skin rash or any other allergic reaction. Although rare, serious and occasionally fatal allergic reactions have been reported, some after only one dose. Signs of an impending reaction include:
- Difficulty swallowing;
- Hives;
- Itching;
- Rapid heartbeat;
- Shortness of breath;
- Swelling of the face and throat;
- Tingling;

Antibiotic

Many common infections in humans are caindicated by single cell living organisms called bacteria. Bacteria invade the body, and then grow, multiply, and spread. drugs that control and eradicate these bacteria are called antibiotics. Ofloxacin is an antibiotic that stops bacteria multiplication by inhibiting the reproduction and repair of their genetic material (DNA).

Indications

Gonorrhoea
Infection of the bladder or tubes that pass urine (urinary tract infection)
Infection of the blood (septicaemia or blood poisoning)
Infection of the lungs and airways (chest or lower respiratory tract infection)
Infections of the sex organs and organs associated with urination (genito-urinary infections)
Skin or soft tissue infections

Ofloxacin is indicated to treat pneumonia and bronchitis caindicated by Haemophilus influenzae and Streptococcus pneumoniae. Ofloxacin is also indicated in treating skin infections caindicated by staphylococcus aureus, and streptococcus pyogenes bacteria. Ofloxacin is indicated to treat sexually transmitted diseases, such as gonorrhea and chlamydia, but is not effective against syphilis. Ofloxacin is often indicated to treat urinary infections and prostate infections caindicated by E. Coli. Some strains of streptococcus, enterococcus, and anaerobic bacteria are resistant to ofloxacin.

Side effects


Abdominal pain;
Abnormal movements of the hands legs face neck and tongue eg tremor twitching rigidity (extrapyramidal effects);
Abnormal or bitter taste;
Allergic reactions such as hives and anaphylaxis (shock);
Anxiety;
Confusion;
Diarrhoea;
Difficulty sleeping;
Disturbance in taste;
Disturbed sleep;
Dizziness;
Drowsiness;
Euphoria;
Excessive sweating or disturbed sleep;
Fast or fluttering heartbeat;
Feeling anxious;
Feeling or being sick;
Hallucinations;
Headache;
Headaches;
Hot flushes;
Insomnia;
Itching (pruritus);
Itching of genital area in women;
Itching;
Itchy rash;
Loss of appetite;
Loss of contact with reality (psychosis);
Nausea and vomiting;
Nausea;
Numbness;
Rash;
Restlessness;
Shaking;
Upset stomach;
Vaginal inflammation;
Vaginitis in women;
Vomiting;

Forms

Tablets: 200 milligrams,
Tablets: 300 milligrams,
Tablets: 400 milligrams.

Dosages

Ofloxacin TABLETS

Worsening of Chronic Bronchitis

The usual dose is 400 milligrams every 12 hours for 10 days, for a total daily dose of 800 milligrams.

Pneumonia

The usual dose is 400 milligrams every 12 hours for 10 days, for a total daily dose of 800 milligrams.

Gonorrhea

The usual dose is 400 milligrams taken once.

Sexually Transmitted Infections of the Cervix or Urethra

The usual dose is 300 milligrams every 12 hours for 7 days, for a total daily dose of 600 milligrams.

Pelvic Inflammatory Disease

The usual dose is 400 milligrams every 12 hours for 10 to 14 days, for a total daily dose of 800 milligrams.

Mild to Moderate Skin Infections

The usual dose is 400 milligrams every 12 hours for 10 days, for a total daily dose of 800 milligrams.

Bladder Infections

The usual dose is 200 milligrams every 12 hours for a total daily dose of 400 milligrams. This dose is taken for 3 days for infections due to E. coli or K. pneumoniae. For infections due to other microbes, Ofloxacin is taken for 7 days.

Complicated Urinary Tract Infections

The usual dose is 200 milligrams every 12 hours for 10 days, for a total daily dose of 400 milligrams.

Prostatitis

The usual dose is 300 milligrams every 12 hours for 6 weeks, for a total daily dose of 600 milligrams.

Ofloxacin OTIC SOLUTION

Otitis Externa (Swimmer's Ear)

For adults and children over 13, the usual dose is 10 drops in the affected ear once a day for 7 days. For children from 1 to 12 years of age, the usual dose is 5 warmed drops in the affected ear once a day for 7 days.

Acute Otitis Media (Severe Middle Ear Infection) in Children with Ear Tubes

For children from 1 to 12 years of age, the usual dose is 5 warmed drops in the affected ear 2 times a day for 10 days.

Chronic Otitis Media with Perforated Eardrum and Pus

For adults and children over 12, the usual dose is 10 warmed drops in the affected ear 2 times a day for 14 days.


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