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Generic Name: Minocycline

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Minocycline contains the active ingredient minocycline hydrochloride, which belongs to a group of antibiotics called the tetracyclines. Minocycline is indicated to treat infections caindicated by bacteria.

Minocycline works by interfering with the ability of bacteria to produce proteins that are essential to them. Without these proteins the bacteria cannot grow, multiply and increase in numbers. Minocycline therefore stops the spread of the infection and the remaining bacteria are killed by the immune system or eventually die.

Minocycline is a broad spectrum antibiotic that is active against a wide variety of bacteria. However, some strains of bacteria have developed resistance to this antibiotic, which has reduced its effectiveness for treating some types of infection. Minocycline is indicated to treat infections caused by susceptible bacteria, which may affect:
- Ear;
- Eye;
- Genitals (eg gonorrhoea urethritis prostatitis pelvic inflammatory disease);
- Lungs (eg bronchitis pneumonia lung abcess nocardiosis);
- Nose;
- The skin;
- Throat;
- Urinary tract;

Minocycline may also be indicated to prevent infections before and after surgery.

To make sure the bacteria causing an infection are susceptible to minocycline your doctor may take a tissue sample, for example a swab from the infected area, or a urine or blood sample.

Minocycline is also indicated to treat acne, as Minocycline is active against the bacteria associated with acne, Propionebacterium acnes. This is a common type of bacteria that feeds on sebum produced by the sebaceous glands in the skin. It produces waste products and fatty acids that irritate the sebaceous glands, making them inflamed and causing spots. By controlling bacterial numbers, minocycline brings the inflammation of the sebaceous glands under control, and allows the skin to heal.

Minocycline is indicated to treat various types of bacterial infections by killing or stopping the growth of the bacteria.

Even if your condition has improved Minocycline is important to complete the indicated course of minocycline.

The most common sides are nausea, vomiting, diarrhoea and headache. These may improve after a few days once your body adjusts to the new drug.

Minocycline is indicated to treat various types of bacterial infections by killing or stopping the growth of the bacteria. Minocycline is particularly useful for treating skin conditions, such as acne.


Minocycline is an antibiotic indicated to treat a wide variety of bacterial infections including acne.


Minocycline is a form of the antibiotic tetracycline.

Minocycline is given to help treat many different kinds of infection, including:

Amebic dysentery
Gonorrhea (when penicillin cannot be given)
Respiratory infections such as pneumonia
Rocky Mountain spotted fever
Syphilis (when penicillin cannot be given)
Urinary tract infections, rectal infections, and infections of the cervix caindicated by certain microbes

To help clear up your infection completely, keep taking Minocycline for the full time of treatment, even if you begin to feel better after a few days. Minocycline, like other antibiotics, works best when there is a constant amount in the body. To help keep the level constant, take the doses at evenly spaced times around the clock.

It's important to take Minocycline exactly as your doctor prescribes. Skipping doses or not completing the full dosage schedule may decrease the drug's effectiveness and increase the chances of bacterial resistance to Minocycline and similar antibiotics.


Acne vulgaris
Eye infections
Infections of the ears, nose or throat
Infections of the urinary tract
Inflammation of the prostate gland due to infection (prostatitis)
Inflammation of the urethra due to infection (urethritis)
Pelvic inflammatory disease
Prevention of infections following surgery
Skin or soft tissue infections

Minocycline may be taken with food or on an empty stomach. Take each dose by mouth with a full glass (8 oz or 240 milliliters) of water unless your doctor directs you otherwise. Do not lie down for 30 minutes after taking this drug. Take Minocycline 2-3 hours before or after taking any medications containing magnesium, aluminum, or calcium. Some examples include quinapril, certain forms of didanosine (e.g. chewable/dispersible buffered tablets or pediatric oral solution), vitamins/minerals, and antacids. Sucralfate, bismuth subsalicylate, iron, and zinc are also included. These medications bind with minocycline preventing its full absorption. Antibiotics work best when the amount of drug in your body is kept at a constant level. Do this by taking the medication at evenly spaced intervals throughout the day and night. Continue to take Minocycline until the full indicated amount is finished even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow resulting in a relapse of the infection.

Minocycline has been indicated for your current condition only. Do not use it later for another infection or give it to someone else. A different medication may be necessary.

Side effects

Abdominal cramping;
Abnormal reaction of the skin to light usually a rash (photosensitivity);
Balance problems involving the inner ear (vertigo);
Blood disorders;
Bowel infection resulting in inflammation of the bowel lining (pseudomembranous colitis);
Difficulty or pain when swallowing (dysphagia);
Difficulty swallowing;
Discolored skin or tooth enamel;
Heart inflammation;
Inflamed mouth or tongue;
Inflammation of the pancreas (pancreatitis);
Joint stiffness or swelling;
Kidney disorders;
Liver disorders;
Loss of appetite;
Mental changes;
Mild increase in pressure within the skull (benign intracranial hypertension);
Muscle pain;
Nausea (feeling sick) or vomiting (being sick);
Nausea and vomiting;
Overgrowth of the yeast candida which may cause infection such as thrush;
Peeling skin;
Ringing in the ears;
Sensation of ringing or other noise in the ears (tinnitus);
Sensitivity to light;
Severe allergic reactions;
Severe dizziness;
Shortness of breath;
Skin reactions such as rash and itch;
Skin reactions;
Sore throat;
Staining of skin nails teeth sweat tears eyes breast milk (see warning above);
Stomach pain;
Stomach upset;
Swelling of face and neck;
Swollen lymph nodes;
Swollen mouth and throat;
Trouble breathing;
Vaginal inflammation;
Vision changes;
Yellowing of the eyes or skin;



The usual dosage of Minocycline is 200 milligrams to start with, followed by 100 milligrams every 12 hours. If you need to take more frequent doses, your doctor may prescribe two or four 50-milligram capsules initially, and then one 50-milligram capsule 4 times daily.

The dosage and the length of time you take the drug can vary according to your condition and the specific infection.


The usual dosage of Minocycline is 4 milligrams per 2.2 pounds of body weight to start, followed by 2 milligrams per 2.2 pounds every 12 hours, up to the usual adult dose.