Flagyl dosage.

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Flagyl dosage.

ADULT

Anaerobic Bacterial Infections

The usual adult oral dosage is 7.5 mg per 2.2 pounds of body weight every 6 hours.

Acute Intestinal Amebiasis (Acute Amebic Dysentery)

The usual dosage is 750 mg taken by mouth 3 times daily for 5 to 10 days.

Trichomoniasis

One-day treatment: 2 gr of Flagyl, taken as a single dosage or divided into 2 doses (1 gr each) taken in the same day.
Seven-day course of treatment: 250 mg 3 times daily for 7 consecutive days.

Trichomoniasis in the Female

One-day treatment-two grams of Flagyl, given either as a single dose or in two divided doses of one gram each given in the same day.

Seven-day course of treatment-250 mg three times daily for seven consecutive days. There is some indication from controlled comparative studies that cure rates as determined by vaginal smears, signs and symptoms, may be higher after a seven-day course of treatment than after a one-day treatment regimen.

The dosage regimen should be individualized. Single-dose treatment can assure compliance, especially if administered under supervision, in those patients who cannot be relied on to continue the seven-day regimen. A seven-day course of treatment may minimize reinfection by protecting the patient long enough for the sexual contacts to obtain appropriate treatment. Further, some patients may tolerate one treatment regimen better than the other.

When repeat courses of the drug are required, it is recommended that an interval of four to six weeks elapse between courses and that the presence of the trichomonad be reconfirmed by appropriate laboratory measures. Total and differential leukocyte counts should be made before and after re-treatment.

Trichomoniasis in the Male

Treatment should be individualized as for the female.

Amebic Liver Abscess

The usual dosage is 500 mg or 750 mg taken by mouth 3 times daily for 5 to 10 days.

Urogenital trichomoniasis
200 mg, three times daily, for 7 days OR 2 g stat. (Sexual partners should also be treated).

Surgical prophylaxis
1 g suppository (At diagnosis/before surgery and every 8 hours for 48 hours after surgery).

Surgical prophylaxis
400 mg (taken 1-2 hours before surgery & repeated every 8 hours for 24 hours).

Invasive intestinal disease in susceptible patients
800 mg, three times daily, for 5 days.

Intestinal disease in less susceptible patients; chronic amoebic hepatitis
400 mg, three times daily, for 5-10 days.

Giardiasis
2 g, once daily, for 3 days.

Elective colonic surgery
1 g suppository, every 8 hours for 48 hours before AND after surgery.

Elderly patients
Pharmacokinetics may be disturbed, therefore monitoring of serum levels should guide dose adjustment.

Bacterial Vaginosis
400 mg, three times daily, for 7 days OR 2 g stat.

Asymptomatic cyst passes
400-800 mg, three times daily, for 5-10 days.

Anaerobic infections
400 mg, three times daily, for 7 days.

Amoebic liver abscess, extra-intestinal amoebiasis
400-800 mg, three times daily, for 5-10 days.

Acute ulcerative gingivitis
200 mg, three times daily, for 3 days.

CHILDREN

Amebiasis

The usual dose is 35 - 50 mg for each 2.2 pounds of body weight per day, divided into 3 doses taken for 10 days.

Surgical prophylaxis
500 mg suppository (At diagnosis/before surgery and every 8 hours for 48 hours after surgery).

Surgical prophylaxis
7-12 yrs 200-400 mg; 1-7 yrs: 100-200 mg (taken 1-2 hours before surgery & repeated every 8 hours for 24 hours).

Invasive intestinal disease in susceptible patients
7-12 yrs: 400 mg three times daily; 1-7 yrs 200 mg three times daily.

Intestinal disease in less susceptible patients; chronic amoebic hepatitis
7-12 yrs: 200 mg three times daily; 1-7 yrs: 100 mg three times daily.

Giardiasis
7-12 yrs: 1 g once daily; 3-7 yrs: 600 mg; 1-3 yrs: 400 mg.

Elective colonic surgery
500 mg suppository, every 8 hours for 48 hours before AND after surgery.

Asymptomatic cyst passes
7-12 yrs: 200-400 mg three times daily; 1-7 yrs: 100-200 mg three times daily.

Amoebic liver abscess, extra-intestinal amoebiasis
7-12 yrs: 200-400 mg, three times daily; 1-7 yrs: 100-200 mg three times daily.

Anaerobic infections
7-12 yrs: 200 mg three times daily; 3-7 yrs: 100 mg three times daily; 1-3 yrs: 100 mg three times daily.

Acute ulcerative gingivitis
3-12 yrs: 100 mg three times daily; 1-3 yrs: 50 mg three times daily.