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Cefuroxime


Generic Name: Cefuroxime

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Tablets

Zinacef injection contains the active ingredient cefuroxime, which is a type of drug called an antibiotic. Cefuroxime is a type of antibiotic called a cephalosporin. These antibiotics are related to penicillin. Cefuroxime is indicated to treat infections caindicated by bacteria.

Cefuroxime works by interfering with the ability of bacteria to form cell walls. The cell walls of bacteria are vital for their survival. They keep unwanted substances from entering their cells and stop the contents of their cells from leaking out. Cefuroxime impairs the bonds that hold the bacterial cell wall together. This allows holes to appear in the cell walls and kills the bacteria.

Cefuroxime is a broad-spectrum antibiotic that kills a wide variety of bacteria that cause a wide variety of commonly-occuring infections. Cefuroxime is given by mouth to treat infections of:
- Ears;
- Nose and throat;
- Skin and soft tissue;
- The upper and lower airways;

Cefuroxime may also be indicated to treat:
- Certain sexually-transmitted infections;
- Lyme disease;
- Urinary tract infections;

Cefuroxime injection is indicated to treat more serious infections, and when drugs cannot be taken by mouth. Cefuroxime is also indicated to prevent infections following various different types of surgery.

The injection is administered either into a muscle (intramuscularly) or a vein (intravenously).

To make sure the bacteria causing an infection are susceptible to cefuroxime your doctor may take a tissue sample, for example a swab from the throat or skin, or a urine or blood sample.

This belongs to the group of drugs known as antibiotics.

Cefuroxime is indicated to treat various types of bacterial infections by killing or stopping the growth of the bacteria.

Cefuroxime is available in capsule, oral liquid and injection form.

Antibiotic

Cefuroxime is a semisynthetic cephalosporin antibiotic, chemically similar to penicillin. Cefuroxime is effective against a wide variety of bacteria organisms, such as:
- E coli;
- Haemophilus influenzae;
- Ngonorrhoeae;
- Staphylococcus aureus;
- Streptococcus pneumoniae;

Antibiotic


Cefuroxime, a cephalosporin antibiotic, is indicated for mild to moderately severe bacterial infections of:
- Ears;
- For gonorrhea;
- Lungs;
- Sinuses;
- Skin;
- The throat;
- Urinary tract;
Cefuroxime tablets are also indicated in the early stages of Lyme disease.

If you are allergic to either penicillin or cephalosporin antibiotics such as:
- Keflex;
- Cefzil;
- Ceclor;
consult your doctor before taking Cefuroxime. There is a possibility that you are allergic to both types of medication; if a reaction occurs, it could be extremely severe. If you take the drug and develop:
- A pounding heartbeat;
- A skin rash;
- Hives;
- Shortness of breath;
seek medical attention immediately.

Indications

Bacterial infections of the lungs and airways (respiratory tract), eg:
- Pneumonia;
- Lung abscess;
- Acute bronchitis;
Bacterial infection of: the ears, nose or throat, eg:
- Laryngitis;
- Pharyngitis;
- Sinusitis;
- Tonsillitis;
Bacterial infections of the urinary tract, eg: cystitis, kidney infections (pyelonephritis)
Gonorrhoea
Pelvic inflammatory disease
Bacterial infections of the skin or soft tissue, eg:
- Wound infections;
- Peritonitis;
- Erysipelas;
- Cellulitis;
Bacterial infections of bones or joints, eg osteomyelitis, septic arthritis
Bacterial meningitis
Blood poisoning (septicaemia)
Preventing infections following:
- Pelvic;
- Oesophageal;
- Lung (pulmonary);
- Heart (cardiac);
- Bone (orthopaedic);
- Blood vessel (vascular) surgery;
- Abdominal;

Cefuroxime is effective against susceptible bacterias causing infections of:
- Bronchitis;
- Laryngitis;
- Pneumonia;
- The middle ear;
- Throat infections;
- Tonsillitis;

Cefuroxime is also indicated in treating:
- Gonorrhea;
- Skin infections;
- Urinary tract infections;

Additionally, Cefuroxime is useful in treating acute bacterial bronchitis in patients with chronic obstructive pulmonary disease (COPD).

Side effects


Abdominal pain;
Allergic skin reactions;
An extreme allergic reaction (anaphylaxis);
Confusion;
Diaper rash in infants;
Diarrhea;
Diarrhoea;
Disturbances in the normal numbers of blood cells in the blood;
Disturbances of the gut such as diarrhoea nausea vomiting abdominal pain;
Dizziness;
Feeling or being sick;
Headache;
Hives;
Hyperactivity;
Inflammation of the kidneys (nephritis);
Mouth ulcers;
Muscle tightness;
Nausea;
Nervousness;
Overgrowth of the yeast candida with prolonged use (this may cause thrush infections);
Pain or inflammation at the injection site;
Problems sleeping;
Rash;
Skin rash;
Temporary rise in liver enzymes;
Tummy pains;
Vaginitis;
Vomiting;
Yellowing of the skin and eyes (jaundice);

Forms

Tablets: 125 milligrams,
Tablets: 250 milligrams,
Tablets: 500 milligrams.
Suspension: 125 milligrams per 5 milliliters teaspoon.

Dosages

ADULTS

The usual dose for adults and children 13 years and older is 250 milligrams, 2 times a day for up to 10 days. For more severe infections the dose may be increased to 500 milligrams, 2 times a day.

Throat and Tonsil Infections

The usual dose is 250 milligrams 2 times a day for 10 days.

Sinus Infection

The usual dose is 250 milligrams 2 times a day for 10 days.

Bronchitis

The usual dose is 250 or 500 milligrams 2 times a day for 5 to 10 days.

Skin Infections

The usual dose is 250 or 500 milligrams 2 times a day for 10 days.

Urinary Tract Infection

The usual dose is 250 milligrams, 2 times a day for 7 to 10 days.

Gonorrhea

The usual treatment is a single dose of 1 gram.

Early Lyme Disease

The usual dosage is 500 milligrams taken twice a day for 20 days.

CHILDREN

Cefuroxime oral suspension may be given to children ranging in age from 3 months to 12 years.

Your doctor will determine the dosage based on your child's weight and the type of infection being treated. Cefuroxime oral suspension is given twice a day for 10 days. The maximum daily dose ranges from 500 to 1000 milligrams.

For children who are able to swallow tablets whole, the usual dosage for ear infection or sinus infection is 250 milligrams 2 times a day for 10 days.


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